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Since the data used were all from public databases, patient consent or ethics committee approval were not required

mode 2, direct GPX4 inhibition using nanomaterials or nanodrugs ( Mode 1 (direct administration of GPX4 inhibitors via nano-delivery systems): In a study, a nanomaterial scaffold was incorporated with three components (small molecule GPX4 inhibitor sorafenib, Fe 3+ and tannic acid)

All those findings highlight the potential of DNA-TG as a promising inclusive marker for toxicity in thiopurine-treated patients, especially those with NUDT15 variants