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Skin and Aesthetics Healthy aging and wellness specialist, Eric Nager, M.D

3:473 and Mamling et al., 2002, Trends Biochem Sci 27:514-520

However, this balance can be shifted toward the pro-oxidants when production of oxygen species is increased greatly (eg, following ingestion of certain chemicals or drugs) or when levels of antioxidants are diminished (eg, by inactivation of enzymes involved in disposal of oxygen species and by conditions that cause low levels of the antioxidants mentioned above)