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Metabolic orchestration driven by GGCT: diverting glutamine to glutathione biosynthesis while enhancing glucose anaplerosis for tumor proliferation Cell Death & Disease Glutathione Synthesis in Cancer Cells Biochemistry (Moscow) Springer Nature Link Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes Cell Biology and Toxicology Springer Nature Link Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Catabolism of extracellular glutathione supplies cysteine to support tumours Nature Glutaredoxin catalysis requires two distinct glutathione interaction sites Nature Communications

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It holds this title because it is found in high concentrations in nearly every cell

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Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF(high) neutrophils

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Therefore, it could be concluded that HLEA-P1 promotes stress resistance by activating DAF-16 transcription factor of IIS pathway rather than SKN-1 transcription factor

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Importantly, these potential off-target effects do not negate our overall conclusion regarding the pivotal involvement of LRP6 in the pathological process

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The x cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: Yet another cytotoxic anticancer approach

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