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Enhancing doxorubicin efficacy through inhibition of aspartate transaminase in triple-negative breast cancer cells

doi: 10.1017/neu.2023.21 76 ZainalNHNewmanMG

Nuclear TRIM59 then promotes ubiquitination and degradation of the tumor-suppressive histone variant macroH2A1, causing STAT3 activation and tumorigenicity (Fig