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Photothermal Fe(3)O(4) nanoparticles induced immunogenic ferroptosis for synergistic colorectal cancer therapy

Trujillo-Hernandez JA, Bariat L, Enders TA, Strader LC, Reichheld J-P, Belin C (2020) A glutathione-dependent control of IBA pathway supports Arabidopsis root system adaptation to phosphate deprivation

Without adequate glutathione stores, Phase 1 toxic intermediates accumulate in the liver and bloodstream, causing severe systemic inflammation and triggering hypersensitivity reactions commonly seen in patients with complex chronic illnesses

10.4110/in.2024.24.e3 Immune Netw

The ROS generated from aerobic respiration caused a cumulative oxidative damage in macromolecules, including lipids, DNA, and proteins, which subsequently lead to cells death (Scheibye-Knudsen et al., 2015), and affect the healthspan of numerous principal organ systems (Dai et al., 2014)

This leads to promoting osteoblast differentiation and inhibiting RANKL-mediated osteoclastogenesis [34, 35], thus maintaining bone remodelling homeostasis