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These reactions are catalyzed mainly by glutathione peroxidases (GPXs), a selenium-dependent enzyme family, and peroxiredoxins (PRDXs), which often function in concert with their reducing partners thioredoxins (TXNs, also known as TRXs) 1,2

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When standard, unmodified glutathione is taken orally, it faces a harsh and destructive environment in the gastrointestinal tract

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1997.View Abstract [2] Gul M, Kutay FZ, Temocin S, Hanninen O