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NAD+ therapy should be used as part of a comprehensive recovery plan that includes counseling, behavioral therapy, and other support services

Diabetes Care 27:21782183 Ziegler D, Low P, Litchy W, Boulton AJ, Vinik AI, Freeman R, Samigullin R, Tritschler H, Munzel U, Maus J, Schtte K, Dyck PJ (2011) Efficacy and safety of antioxidant treatment with -lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial

Our findings demonstrate that the antiproliferative synergistic effects of the combined treatment are independent of the CMS and microsatellite stability status (Supplementary Fig