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Gap junction dysfunction reduces acetaminophen hepatotoxicity with impact on apoptotic signaling and connexin 43 protein induction in rat

Changes in cardiovascular risk factors were mostly favorable, and adverse effects were mild in this study

doi: 10.1073/pnas.0605296103 117 CampbellDBDOronzioRGarbettKEbertPJMirnicsKLevittPet al

Phase II study of disulfiram and cisplatin in refractory germ cell tumors

The transfection of pHDAC2 combined with the elimination of ROS by MnPD exhibited a significant enhancement of intracellular HDAC2 expression levels, suggesting that the multi-antioxidative activity of MnPD plays a crucial role in the expression of HDAC2