In many cases, abundant melanin is present within melanophages in the papillary dermis or superficial lamina propria, so-called pigment incontinence
The American College of Surgeons Commission on Cancer and the American Cancer Society
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Neuroendocrine Research: Probe melanocortin system roles in energy balance, thermogenesis, and hypothalamic regulation of appetite PubMed
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Because wide excisions involve the removal of a larger area of skin and tissue often several centimeters longthe closure can be tight , and the healing process may take longer than with smaller procedures