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Evidence from animal studies suggests that the effects of GCs on LTP and memory follow an inverted U-shaped dose-response relationship, with moderate physiological levels supporting synaptic plasticity and memory consolidation, whereas both insufficient and excessive GC exposure are associated with impairment (Pavlides et al., 2002

Statistical heterogeneity was assessed for key metabolites of the -glutamyl cycle, trans-sulphuration pathway and GSH:GSSG using the Review Manager 5 (RevMan) statistical software [58]