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Mattingly SM, Martinez G, Young J, Cain MK, Striegel A

However, stopping Semaglutide is a safe and common practice that doesn't involve serious health risks

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TMAO has also been shown to induce inflammatory markers in mice and in human aortic endothelial cells and vascular smooth muscle cells owing to activation of MAPK, extracellular signal kinase, and NF-B signaling cascade, along with promoting the recruitment of activated leukocytes to endothelial cells

Nonetheless, further studies are required to investigate the underlying molecular mechanisms to understand its therapeutic effects better