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Previous research has demonstrated an association between PFis and changes in PF elasticity and thickness 16

Afterwards, cells were washed twice with PBS, and then incubated for 20 min at room temperature with Rho123 diluted in respiration buffer (130 mM KCl, 5 mM K 2 HPO 4 , 20 mM MOPS, 2.5 mM EGTA, 3 mM succinate, 0.1% BSA, adjusted to pH 7.15 with KOH) to a final concentration of 1 M

Regulation of myocardial carbohydrate metabolism under normal and ischemic conditions: Potential for pharmacological interventions

The frequency of TM6SF2 CC (wild type), TM6SF2 CT (heterozygous), and TM6SF2 TT (homozygous) genotypes were 79-82%, 15-21% and 0-3% across 3 treatment arms

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