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The second generation (20112018) introduced humanized antibodies, cleavable linkers, and engineered conjugation sites, improving DAR consistency (typically ~3-4) and enabling the use of potent microtubule inhibitors like MMAE and DM1

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A common theme for many polyphenols and flavonoids, however, is poor oral bioavailability [103]

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Nat Commun (2016) 7:11457

Exhaled volatile organic compounds in adult asthma: A systematic review