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FXR senses BA levels in hepatocytes and enterocytes

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Challenges in scalable, GMP-compliant manufacturingparticularly batch-to-batch variability in encapsulation efficiency (2194% for PLGA NPs)and long-term biocompatibility assessments (e.g., hepatosplenic accumulation, PEG immunogenicity) remain unresolved

Our liposomal formulation, in which sheaths of phospholipid protect the ALA, dramatically improve alpha lipoic acid absorption

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