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Trends Endocrinol Metab (2022) 33(4):24765

This curation strategy included more than 430 genes for which loss-of-function and gain-of-function studies have demonstrated their requirement in the main processes of oligodendrogenesis (that we categorized in specification, proliferation, migration, survival, differentiation, myelination, and remyelination)

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Mutations in neuronal synaptic proteins include post-synaptic proteins such as neuroligins (NLGNs) and pre-synaptic proteins such as neurexins (NRXN), SHANK, and GRIP1 [73]

Moreover, the systemic elevation of Gln improves insulin sensitivity and restores glucose homeostasis in mouse models of obesity

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