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But it also means more injections, more complex dosing schedules, and more potential drug interactions

Abundant evidence exists that many protein, lipid, and DNA markers of oxidative stress are increased in cultured vascular cells exposed to high glucose levels and in vascular tissues from animals and human subjects with diabetes [13]

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Spermatogonial stem cell (SSC) transplantation and testicular tissue grafting are promising experimental therapies aiming to restore spermatogenesis

Accordingly, most if not all GSTLs, GHRs, GSTOs and DHARs characterized so far exhibit thiol-transferase and DHAR activities but no transferase, peroxidase or isomerase activities except for a Beta GST from Proteus mirabilis , which possesses a slight peroxidase activity on cumene hydroperoxide ( k cat around 0.01 s 1 ) and a non-negligible GSH transferase activity on CDNB ( k cat around 2 s 1 ) (Table 5) (Federici et al., 2010)

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