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However, very high doses from supplements or injections may lead to certain side effects in some individuals

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Given that the status of these micronutrients in patients with T2DM is already likely to be suboptimal and that these deficiencies are variously associated with diabetic complications such as compromised endothelial, microvascular, vascular and neurological function, 38,43,4649,80,85,9597 it may be appropriate to consider supplementation where appropriate to mitigate these negative impacts of metformin

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Access this article Similar content being viewed by others References Jutel M, Agache I, Zemelka-Wiacek M, Akdis M, Chivato T, del Giacco S et al (2023) Nomenclature of allergic diseases and hypersensitivity reactions: adapted to modern needs: an EAACI position paper