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SARS-CoV-2 infection reprograms host folate and one-carbon metabolism at the PTM level to support de novo purine synthesis for replication of viral genome, through bypassing the viral shutoff of host translation 37

Disrupting SV release leads to a notable reduction in myelin sheaths while stimulating neurons promotes myelin sheath production in an activity-dependent manner based on SV release (Mensch et al., 2015)

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Ann Rheum Dis (2006) 65 Suppl 3:iii89

62 , e202213922 (2023)