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Description

Translational research must rigorously transition toward pre-symptomatic pharmacological interventions using advanced humanized transgenic models, such as the YG8sR and the more recently developed YG8-800 lines [129]

45 l of the eluted fraction were precipitated with 4 volumes of acetone at 20 C overnight whereas 5 l were used for quality control (Western Blot)

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Such studies hold significant promise for informing the development of novel therapeutic strategies and providing critical frameworks for treatment efficacy evaluation