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bootstrapped 95% CI [0.14, 2.46]) and insula (b = 1.80, 95% CI [0.24, 3.35], p =.025

This mechanism creates a gradient of concentration that enables the ongoing consumption of SFN while maintaining a balance in its export (94)

Gut microbiota composition can modulate this process for example, certain microbial metabolites might affect -syn misfolding or clearance [94]

benefit: FDA only looked at risk, ignored benefits Off-label use: Doctors prescribe drugs off-label all the time Patient access: People are suffering and need options Regulatory capture: Big Pharma doesn't want cheap peptides competing The problem with these arguments: It's NOT off-label use Off-label only applies to FDA-approved drugs

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