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coli also contains protein disulfide isomerases, the Dsb enzymes, which have thioredoxin-like folds and act as strong thiol:disulfide oxidants (Missiakkas and Raina, 1997

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Furthermore, the absorption of CDCZA nanoparticles by Eca-109 cells increased over time, as shown by flow cytometry analysis (Figure S8B)

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The site-specific incorporation of MP and MOP modifications has been used to reduce ASO protein binding since the PS backbone is negatively charged, whereas alkylphosphonate linkages are charge neutral