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10.1097/00003086-199404000-00046 24 DamienC

10.2741/2070 Front

Several non-pharmacological approaches have also been studied, including physical rehabilitation, hypoxia/ischemia, and hypothermia

Larger-sample studies are needed to verify these findings

F.KieperN.MaurerB.WaakJ.et al

Classic example with conjugation occurring after introduction of a nucleophilic site (phenol) Kamata et al Drug Metabolism Disposition 2006 Many compounds or drugs contain functional groups that can be directly conjugated and thus do notrequire Phase I metabolism to create handles (nucleophiles) for conjugation.Ciprofloxacin Propranolol BilirubinDiflunisal Acetaminophen Thyroxine (T4)Q