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Integration of Gene Replacement with Multimodality Cancer Treatment

Reduced consumption of NADPH has been observed when fatty acid synthesis is inhibited by AMP-activated protein kinase (AMPK) via inhibition of acetyl-coenzyme A carboxylase (55)

Baseline PS exposure increased modestly but significantly over time in both iRPMI alone (T 1h =0.1% and T 48h =0.6%

A.PopescuG.et al (2010)

Currently, there is a lack of validated biomarkers that can accurately measure the clinically relevant redox state of a tumor or an immune cell in vivo