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It reduces the number of active melanocytes and disrupts melanin synthesis at a deeper level

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The histological analysis was performed using a high power objective (x63) in the microscope ZEISS AXIOSKOP 2, by counting cells in three areas with a minimum of approximately 100 m 2 , using three distinct serial sections (50 m interval between sections) per animal, for five different animals

Specific candidate Rab-binding proteins (open arrowheads/arrows) were excised and identified by mass spectrometry

doi: 10.1136/bmjopen-2016-014613 62 GuanWJGaoYHXuGLinZYTangYLiHMet al

Conventional Hyperthyroid Treatment Conventional hyperthyroid treatment involves the use of anti-thyroid medications (methimazole and propylthiouracil), radioactive iodine ablation (destruction) of the thyroid gland, or thyroidectomy (surgical removal of the thyroid gland)