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et al, 2018 (84) of ten randomized placebo-controlled trials involving 796 patients showed short-term (3 months) efficacy of Se supplementation on fT4 and fT3 levels in patients with GD

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The trial design included a core study phase consisting of a four-week screening period, followed by a four-week baseline phase where participants received only a placebo in a single-blind manner, and then a 24-week randomized treatment phase, where participants received either bremelanotide or placebo [1]

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