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Course of iron parameters in HFE-hemochromatosis patients during initial treatment with erythrocytapheresis compared to phlebotomy

These bioactive compounds play crucial roles in maintaining metabolic homeostasis, immune regulation, and endocrine function through multiple interconnected mechanisms ( At the mechanistic level, dysregulation of SCFAs contributes to the pathogenesis of PCOS through multiple pathways: first, decreased SCFAs (including butyrate) reduce the expression of intestinal tight junction proteins, increasing gut permeability and allowing LPS translocation into circulation, which triggers chronic low-grade inflammation

A real-world prospective cohort study including 2.2 million people demonstrated that the combination of SGLT-i and GLP-1 had better effects on all-cause mortality, MI and admission rate than SGLT-i or GLP-1 alone

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[DOI] [PubMed] Zhang H., Jia H., Liu J., Ao N., Yan B., Shen W., Wang X., Li X., Luo C., Liu J

doi: 10.1038/s41467-022-28720-y 127 MichelsenK