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Capsid-optimized adenovirus-associated virus 8 vectors was used to deliver the CRISPR-CasRx system to pancreatic cancer in situ tumors and patient-derived tumor xenografts, demonstrating that CasRx accurately and efficiently silenced the expression of Kras G12D mutants in pancreatic ductal adenocarcinoma cells guided by Kras G12D -specific gRNA

Probiotics and prebiotics: Present Status and Future Perspectives on Metabolic Disorders

After quality control, the transcriptomes of 40 231 cells (17 814 from pulpitis samples and 22 417 from healthy pulp samples) were obtained

10.1016/j.micres.2013.09.020 212 TuS.XiaoF.MinX.ChenH.FanX.CaoK

nonetheless, they can be equally as debilitating as motor symptoms for many patients

Metformin, a well-established treatment for Type 2 diabetes, has increasingly been applied to address IR in recent years (92)