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One reason for this might be the particular approach of acknowledging this risk and amending oral hygiene instructions accordingly, which can result in the reduction of plaque retention in this area

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Variable modifications included acetylation of the protein N terminus, oxidation of methionine, cyclization to pyroglutamic acid and N-terminal deamidation

Psychiatry 25 , 131147 (2020)

The activation of these events results in an increase in vasoconstriction and the promotion of thrombus formation, which can ultimately lead to the development of atherosclerosis (16)

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