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Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]

With over 1,600 schools spread across five boroughs, the system is made up of approximately 1 million students and staff, making it the largest public school system in the nation

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Any reference to biological activity or potential effects is based solely on preclinical or in vitro findings and should not be interpreted as validated clinical outcomes

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Since some db/db mice succumbed to this treatment probably due to RIF toxicity at 16 mg/kg, we reduced the dose to 8 mg/kg and treated the animals 3 times weekly through oral gavage from day-4 onwards until 8 weeks post-infection