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This effect has also been demonstrated in both in vitro cell culture models and in vivo mouse models

Results can vary, but with regular maintenance, the effects can be long-lasting

ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis

This appears to confirm that impairment of Na + /K + ATPase function is a common mechanism for UV-induced lens cataract (212), while highlighting that in vivo and ex vivo exposure systems can produce conflicting results

In ovarian cancer, these defense systems appear particularly relevant under therapeutic stress