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Colonies with Hif1a KO were selected by flow cytometry single cell sorting and expression validated by immunoblotting

At 60 h-post injection, the mice were sacrificed and the biodistribution determined upon fluorescence imaging of the respective organs

We carefully reviewed canonical marker gene expression on UMAP plots and repeated the steps above a couple of times to ensure that we had filtered out most of the barcodes associated with cell doublets

Patients were classified into IGH and IGL groups according to the cutoff value of intracellular GSH levels

Platelets: no longer bystanders in liver disease

Update on C1 esterase inhibitor in human solid organ transplantation