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217 Among these metabolic pathways, mitochondria, as the major organelles in iron utilization, involved in anabolic and catabolic pathways, play a crucial role in iron and energy metabolism

(Lausanne) 11, 191

A deeper understanding of the biological properties and regulatory mechanisms of NPPCs is crucial for advancing their therapeutic application

The nuclear receptor transcription factor Nurr1 orchestrates DA neuron maturation, functional regulation, and lifelong maintenance, with its expressioninitiating in the VM at embryonic day 10.5 (in mice) and persisting throughout adulthoodmediating perinatal stress response adaptation (Zetterstrm et al., 1996)