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Table I [i] ROS reactive oxygen species, O 2 superoxide radical, mtDNA mitochondrial DNA, 8OHdG 8-hydroxy-2-deoxyguanosine, UCP2 uncoupling protein 2, CYP2E1 cytochrome P450 2E1, NOX NADPH oxidase, MDA malondialdehyde, 4-HNE 4-hydroxynonenal, TGF- transforming growth factor-, H 2 O 2 hydrogen peroxide

Figure 1 3 Regulation of TCM on PCOS PCOS is a prevalent endocrine disorder affecting women of reproductive age, characterized by a range of symptoms including hyperandrogenism, menstrual irregularities, and polycystic ovarian morphology

increased significantly at the time point when severe mechanical allodynia was observed (Brandon-Mong et al., 2020)

Finally, we thank Mercedes Joaquin for her care of the animal colony

However, recent technological advances allow a more comprehensive analysis of enzymatic systems via using the systematic kinetics apparatus that was developed for small molecule reactions, which is expected to provide further insight into the cell's machinery

Now lets look at a different scenario