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Description

Aligning with the plausible development of accelerated aging or neurodegenerative disorder, cognitive impairment is highly prevalent among patients with post-COVID syndrome [8, 10]

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[DOI] [PubMed] [Google Scholar] 265

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On the following day, scopolamine methyl bromide (1 mg/kg body weight, Sigma-Aldrich) was intraperitoneally injected to minimize peripheral cholinergic effects, then 30 min later, pilocarpine hydrochloride (10 mg/kg body weight, Sigma-Aldrich) was administered every 30 min until the animals reached Racine stage 4 or 5 seizures

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the resulting S- substituted cysteinylglycines are cleaved by dipeptidase (Reaction 6A) to yield the corresponding S- substituted cysteines, which may undergo N-acetylation (Reaction 8) or an additional transpeptidation reaction to form the corresponding -glutamyl derivative (Reaction 3A)

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