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Deficiency in vitamin B12 may cause anemia, fatigue, muscle weakness, intestinal problems, nerve damage, and mood disturbances

278 However, in T cells, Asn can enhance the antitumor effect of CD8 + T cells by binding to the SRC family protein tyrosinase LCK and assisting LCK to phosphorylate at Tyr394 and 505, thereby enhancing the activity of Lck starved T cell receptor signaling pathway

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Adeva-Andany M, Souto-Adeva G, Ameneiros-Rodrguez E, Fernndez-Fernndez C, Donapetry-Garca C, Domnguez-Montero A

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9 Acetaminophen-induced liver toxicity has become the most common cause of acute liver failure and the second most common cause of liver failure requiring transplantation