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NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM, the universal methyl donor in cells) to nicotinamide (a form of vitamin B3 and a precursor for NAD+ synthesis), producing 1-methylnicotinamide and S-adenosylhomocysteine (SAH)

These proteins, located in liver cells, help to move various compounds into cells without requiring sodium, including hormones, drugs, toxins, and more

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[PubMed] [Google Scholar] 7.Wang C.C., Xu H., Man G.C., Zhang T., Chu K.O., Chu C.Y., Cheng J.T., Li G., He Y.X., Qin L., et al