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Biomarker-based patient selection, such as circulating oxidative stress markers (e.g., MDA, 8-OHdG), remains speculative and has not been integrated into trial designs

A recent study by Lius team demonstrated that the broad-spectrum DUB inhibitor palladium pyrithione complex (PdPT) promote GPX4 degradation, but proteasome inhibitor bortezomib reverses its effect (Yang L

Mice were housed in appropriate cages with twelve wake-light/sleep-dark cycles and an ambient temperature of 25 0.5 C

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Isorhamnetin Inhibited Migration and Invasion via Suppression of Akt/ERK-Mediated Epithelial-To-Mesenchymal Transition (EMT) in A549 Human Non-small-cell Lung Cancer Cells

I explain each protocol in detail, the rationale behind it, and how the protocol can be adjusted depending on individual needs