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Although AML cells consume more oxygen at the basal metabolic level, the efficiency of ATP generation does not improve because the cells exhibit significant proton leak and poor coupling efficiency (ratio of oxygen consumed for ATP production to oxygen lost in proton leak) (36)

Gill H, Gill B, El-Halabi S, et al

Electron microscopic localization of lacZ expression in the proximal convoluted tubular cells of the kidney in transgenic mice carrying chimeric erythropoietin/lacZ gene constructs

5 BenekosK.KissoudisC.Nianiou-ObeidatI.LabrouN.MadesisP.KalamakiM.et al (2010)

Times of increased stress levels come and go but remain prevalent for specific populations, as not all diseases are preventable (e.g., due to genetics or that many people currently live with NCDs/chronic conditions), and therefore stress management and relief practices (e.g., Red Noses Clowndoctors, Sensory Room Therapy, yoga) hold precious value (400402)

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