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In contrast, although non-antimicrobial sulfonamides are sulfur-based, these medications have a different chemical structure [5]

doi: 10.1016/j.biocel.2020.105876 164 MokEHKLeeTKW

18th Annual Targeted Therapies of Lung Cancer Meeting

33,34 JNK translocates to mitochondria, binds to SH3 homologyassociated Brutons tyrosine kinase (BTK) binding protein (Sab) on the mitochondrial membrane, and subsequently inactivates a proto-oncogene tyrosine-protein kinase (Src) in mitochondria, eventually leading to the dysfunction of the ETC and the increased release of reactive oxygen species (ROS)

doi: 10.1016/j.biopha.2022.113139

It is primarily distributed in northwestern Chinas inland regions (e.g., Xinjiang, Inner Mongolia, Qinghai) and serves as a dominant species in desert and grassland ecosystems [6]