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Dimethyl Fumarate, a Small Molecule for the Treatment of Moderate-to-Severe Psoriasis Professor Antonio Costanzo Psoriasis Pathogenesis and Genetic Pre-Disposition Development of psoriasis occurs due to interactions with epidermal keratinocytes and immune-system cells including T-lymphocytes, antigen-presenting dendritic cells, and neutrophils

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Some patients report subjective improvements in sleep quality or energy levels within the first treatment cycle, while potential effects on longevity markers require longer-term assessment