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Once adapted, TAMs themselves become major ROS producers, primarily through NOX2 activity, using ROS to suppress cytotoxic T cells and NK cells [147, 148]

IECs necrosis has long been associated with the severity of IBD inflammation, and abnormal IEC death can impair intestinal barrier function, exacerbating inflammatory responses [59]

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ALD and ALD+ had higher mortality for both liver (OR=3.45 and OR=2.6* respectively) and non-liver-related hospitalizations (OR = 3.96 and OR = 2.71* respectively) when compared to MASLD

Huang Y, Tan T, Liu L, Yan Z, Deng Y, Li G,