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90 days on, 30 days off) are reported but not scientifically validated

The clinical ramifications of these observations warrant further studies

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J Assist Reprod Genet (2018) 35:47582

112 LuoC.TaoL

As an initiator of the inflammatory cascade, IL-1 induces IL-6 production, thereby amplifying inflammation through T-helper 1 (Th1) and T-helper 17 (Th17) immune responses