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Wang, J., Zhang, A., Ye, M

It is metabolized hepatically and excreted renally, with a half-life of under thirty minutes

Mt nghin cu trn cc t bo da ngi cho thy rng iu tr cc t bo bng chit xut dng x gip ngn nga tn thng t bo lin quan n phi nhim tia cc tm, lo ha v ung th - ng thi kch thch sn xut protein da mi thng qua hot ng chng oxy ha ca n

Hence, it is logical to hypothesize that masking of the terminal NH 2 group by making a labile chemical derivative of INH, i.e., a derivative which can release INH back when exposed to biofluid in gut or blood (owing to hydrolytic activity of esterase/amidase) can limit known metabolic biotransformations of INH (Figure 6)

The Dialcat Consortium Article: PLOS ONE

We posit that the integration of pharmacological treatment with rehabilitation may yield synergistic effects, accelerating cognitive recovery and functional gains (4951)