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Results are expected to be released in late 2024 (9)

Vitamin B12 shots may help reduce the risk of serious conditions such as heart disease and stroke as well as cognitive issues, infertility, and neural tube defects (when mothers have B12 deficiency)

NNMT is an enzyme expressed at particularly high levels in adipose tissue and the liver, where its role is to transfer a methyl group from S-adenosylmethionine (SAM) onto nicotinamide, producing 1-methylnicotinamide as a waste product

Each route has a different evidence base, and non-injectable routes should be treated as historical or limited-evidence context rather than a protocol recommendation

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