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Compared with the TGF- stimulation group, both mRNA and protein levels of the fibrotic markers, including COL1A1, POSTN, and -SMA, were significantly reduced in the group with concurrent TGF- stimulation and GSTM1 overexpression (Fig

This study reports an 'engineering' approach to drug discovery, capitalizing on the modular nature of drug conjugates, that describes the critical importance of a precise understanding of tumour targeting and cellular-based drug release processes