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On this basis, we stated that we anticipate establishing a performance threshold of 75 points for the CY 2025 performance period/2027 MIPS payment year will allow us time to gather additional data on the impacts of new policies on small and rural practices, and to develop strategies to reduce barriers for small practices and solo practitioners participating in MIPS (89 FR 62092)

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Several technical reasons may explain our distinctive findings, including differences in the microbiome sampling site, the limited n per group, singly housing mice, or the use of highly similar lean, Western, and high-fat diets which systematically exchanged fat content with carbohydrate content

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