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The expression of proteins filaggrin (FLG) and loricrin (LOR) was evaluated by immunofluorescence, while the expression of mRNAs FLG and LOR in the skin was measured via qRT-PCR

Lancet 2021 Phase 2 (monotherapy) Lau et al., n=706, 26 weeks

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De Luca C, Lievore G, Bozza D, Buratti A, Cavazzini A, Ricci A, et al

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suggests that The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(II) (GHK-Cu) [may be] a well-[regarded] activator of tissue remodeling, with its mechanistic profile possibly extending beyond simple collagen stimulation