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When the intestinal epithelial barrier function is impaired, under lipopolysaccharide stimulation, nuclear factor kappa B (NF-kB) translocates from the cytoplasm to the nucleus, and stimulates dendritic cells and macrophages to produce pro-inflammatory cytokines and mediators, such as cyclooxygenase-2, TNF- , inducible nitric oxide synthase, and IL-6, which regulate intestinal and systemic inflammation (92)

If you are pregnant, breastfeeding, or are an older adult, talk to your doctor to ensure this therapy is safe for your individual needs

[DOI] [PubMed] [Google Scholar] 53.Qiu Z., Zhou J., Zhang C., Cheng Y., Hu J., Zheng G

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