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10.1128/JVI.02123-09 55 ChangC

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Molecules like the cell cycle protein p21 have been reported to interact directly with GPX4, competitively or allosterically affecting its ubiquitination rate, thereby stabilizing GPX4 and enhancing cellular resistance under oxidative stress (Zheng et al., 2024)

David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity