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Further alterations in intracellular redox balance driven by lower GSH availability induce cell death and enhance T2 signature protein expression We previously demonstrated that 15LO1-PEBP1 complex activation consistently upregulates the expression of T2-signature gene/protein expression, including MUC5AC, periostin (POSTN), and CCL26 (6, 10, 14)

RSL3 suppresses viability in thyroid cancer cell lines To determine whether GPX4 inhibition affects tumor cell viability, we treated PTC cells with various concentrations of RSL3 and performed a cellular viability assay

Bes et al

Step-by-step reconstitution process Start with clean hands and a clean workspace